產(chǎn)品編號(hào) | bs-11482R-Gold |
英文名稱 | Rabbit Anti-Semaphorin 5B/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的跨膜蛋白SEMA5B抗體 |
別 名 | SEM5B_HUMAN; SEMA5B; SEMAG; Semaphorin-5B; Semaphorin 5B; Semaphorin5B; SemG. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, Cow, Horse, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 126kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SEMA5B/Semaphorin 5B (146-195aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA5B (semaphorin-5B), also known as SEMAG, is a 1151 amino acid member of the semaphorin family. Localized to the membrane, SEMA5B is a single-pass type III protein that functions to convey positive axonal guidance cues and can induce calpain-mediated cleavage of calcineurin. Three isoforms exist due to alternative splicing events. Function: May act as positive axonal guidance cues. Subcellular Location: Membrane; Single-pass type III membrane protein. Similarity: Belongs to the semaphorin family. Contains 1 PSI domain. Contains 1 Sema domain. Contains 5 TSP type-1 domains. Database links: Entrez Gene: 54437 Human Omim: 609298 Human SwissProt: Q9P283 Human Unigene: 210870 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |