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產(chǎn)品編號	bsm-30117M-FITC
英文名稱	human CD45RB/FITC
中文名稱	FITC標記人CD45RB單克隆抗體
抗體來源	Mouse
克隆類型	Monoclonal
克隆號	45F2
交叉反應(yīng)
產(chǎn)品應(yīng)用	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
檢測分子量	220
性狀	Liquid
亞型	Mouse IgG2b, κ
純化方法	Affinity purified by Protein G
緩沖液	0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存條件	Store at 2-8℃. Protect from light. Avoid freezing.
注意事項	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產(chǎn)品介紹	CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, na?ve T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from na?ve to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1. SWISS: P08575 Gene ID: 5788

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