| 產(chǎn)品編號 | bs-17135R |
| 英文名稱 | SOX18 Rabbit pAb |
| 中文名稱 | 轉(zhuǎn)錄因子SOX18抗體 |
| 別 名 | HLTS; SOX 18; Sox18; SOX18_HUMAN; SRY(sex determining region Y) box 18; SRY box 18; Transcription factor SOX 18; Transcription factor SOX-18. |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,Cow,Dog,Rhesus monkey) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 41 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SOX18: 101-200/384 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. [provided by RefSeq, Jul 2008] Function: Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site. Subcellular Location: Nucleus. DISEASE: Defects in SOX18 are the cause of hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) [MIM:607823]. Similarity: Contains 1 HMG box DNA-binding domain. Contains 1 Sox C-terminal domain. SWISS: P35713 Gene ID: 54345 Database links: Entrez Gene: 54345 Human Entrez Gene: 20672 Mouse Omim: 601618 Human SwissProt: P35713 Human SwissProt: P43680 Mouse Unigene: 8619 Human Unigene: 264904 Mouse Unigene: 22446 Rat |
| 產(chǎn)品圖片 |
Protein: heart(mouse)cell lysate at 40ug;
Primary: rabbit Anti-SOX18 (bs-17135R) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 41 kD
Observed band size: 41 kD
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