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GPRASP1 Rabbit pAb (bs-16299R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-16299R
英文名稱 GPRASP1 Rabbit pAb
中文名稱 GPRASP1蛋白抗體
別    名 G-protein coupled receptor-associated sorting protein 1; GASP; GASP-1; GASP1; GASP1_HUMAN; Gprasp1; KIAA0443.  
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Sheep,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 120 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPRASP1: 1001-1100/1395 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]

Function:
May modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra.

Similarity:
Belongs to the GPRASP family.

SWISS:
Q5JY77

Gene ID:
9737

Database links:

Entrez Gene: 9737 Human

Omim: 300417 Human

SwissProt: Q5JY77 Human

Unigene: 522729 Human



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