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DGCR2 Rabbit pAb (bs-8258R)  
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產(chǎn)品編號 bs-8258R
英文名稱 DGCR2 Rabbit pAb
中文名稱 DGCR2蛋白抗體
別    名 DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.  
研究領域 心血管  細胞生物  免疫學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Rabbit,Cow,Zebrafish, Orangutan)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 59 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGCR2: 151-250/550 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.

Function:
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.

Subcellular Location:
Membrane; Single pass type I membrane protein.

Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney.

Similarity:
Contains 1 C-type lectin domain.
Contains 1 LDL-receptor class A domain.
Contains 1 VWFC domain.

SWISS:
P98153

Gene ID:
9993

Database links:

Entrez Gene: 9993 Human

Entrez Gene: 13356 Mouse

Entrez Gene: 360742 Rat

Omim: 600594 Human

SwissProt: P98153 Human

SwissProt: P98154 Mouse

SwissProt: Q66HD9 Rat

Unigene: 517357 Human

Unigene: 254515 Mouse



產(chǎn)品圖片
Sample: Lane 1: Human HeLa cell lysates Lane 2: Human MCF-7 cell lysates Primary: Anti-DGCR2 (bs-8258R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 59 kDa Observed band size: 62 kDa
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