| 產(chǎn)品編號(hào) | bs-6334R |
| 英文名稱 | ORP8 Rabbit pAb |
| 中文名稱 | 氧化固醇結(jié)合蛋白8抗體 |
| 別 名 | MST120; MSTP120; ORP 8; OSBP related protein 8; OSBP10; OSBPL8; Oxysterol binding protein like 8; Oxysterol binding protein like protein 8; Oxysterol binding protein related protein 8; OSBL8_HUMAN. |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 101 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ORP8: 121-220/889 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux. Subcellular Location: Endoplasmic reticulum Tissue Specificity: Widely expressed. Similarity: Belongs to the OSBP family. Contains 1 PH domain. SWISS: Q9BZF1 Gene ID: 114882 Database links: Entrez Gene: 114882 Human Entrez Gene: 237542 Mouse Omim: 606736 Human SwissProt: Q9BZF1 Human SwissProt: B9EJ86 Mouse Unigene: 220204 Mouse |
